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An Early Detection System for H5N1 Highly Pathogenic Avian Influenza in Wild Migratory ... usually cause little or no disease. However domestic birds are ...

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Page 1Contact: USDA Press Office (202) 7204623 DOI Press Office (202) 2086416 SCREENING FOR HIGHLY PATHOGENIC H5N1 AVIAN INFLUENZA INMIGRATORY BIRDS An Early Detection System for H5N1 Highly Pathogenic Avian Influenza in Wild Migratory Birds U.S. Interagency Strategic Plan March 2006 Avian influenza (AI) is a virus that is naturally found in wild birds particularly in certain species of waterfowl and shorebirds. Occurrences of an H5N1 highly pathogenic avian influenza(HPAI) virus overseas have heightened concern regarding the potential impact on wild birdsdomestic poultry and human health should it be introduced into the United States. To understand the differences and potential threats to U.S. bird populations this fact sheet provides definitions a historical perspective and an outline of the U.S. Department ofAgriculture (USDA) and U.S. Department of the Interior (DOI) efforts to detect the H5N1 HPAI virus in wild migratory birds. BACKGROUNDABOUT THE VIRUS AI viruses are classified by a combination of two groups of proteins found on the surface of the virus: hemagglutinin proteins (H) of which there are 16 (H1H16) and neuraminidase proteins(N) of which there are 9 (N1N9). There are 144 possible combinations or subtypes based upon this classification scheme. Wild birds in particular certain species of waterfowl and shorebirds are considered to be thenatural reservoirs for avian influenza viruses. These subtypes that naturally occur in wild species usually cause little or no disease. However domestic birds are generally more susceptible toavian influenza virus and mutation or recombination of a virus acquired from wild birds can increase its disease potential in these domestic birds. AI strains also are divided into two groups based on the pathogenicity of the virusthe ability ofthe virus to produce disease.Page 2Low Pathogenicity Avian Influenza (LPAI): Most AI strains are classified as lowpathogenicity and cause few clinical signs in infected birds. LPAI ...

Source: www.nwhc.usgs.gov

 

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